Synthesis, characterization, and analgesic activity of novel schiff base of isatin derivatives
نویسندگان
چکیده
منابع مشابه
synthesis and characterization of some macrocyclic schiff bases
ماکروسیکلهای شیف باز از اهمیت زیادی در شیمی آلی و دارویی برخوردار می باشند. این ماکروسیکلها با دارابودن گروه های مناسب در مکانهای مناسب می توانند فلزاتی مثل مس، نیکل و ... را در حفره های خود به دام انداخته، کمپلکسهای پایدار تولید نمایند. در این پایان نامه ابتدا یک دی آلدئید آروماتیک از گلیسیرین تهیه می شود و در مرحله بعدی واکنش با دی آمینهای آروماتیک و یا آلیفاتیک در رقتهای بسیار زیاد منجر به ت...
15 صفحه اولSynthesis and analgesic activity of novel Hydrazide and Hydrazine derivatives
The uses of non-steroidal anti-inflammatory drugs (NSAIDs) are limited by a variety of side effects. So research on preparing new analgesic agents is important. According to some reports about the analgesic activity of hydrazide and hydrazine derivatives a new series of these compounds were synthesized in order to obtain new analgesic compounds. The final compounds 10a-10e and 15a-15d were pre...
متن کاملSynthesis and analgesic activity of novel Hydrazide and Hydrazine derivatives
The uses of non-steroidal anti-inflammatory drugs (NSAIDs) are limited by a variety of side effects. So research on preparing new analgesic agents is important. According to some reports about the analgesic activity of hydrazide and hydrazine derivatives a new series of these compounds were synthesized in order to obtain new analgesic compounds. The final compounds 10a-10e and 15a-15d were pre...
متن کاملNovel Organotin(IV) Schiff Base Complexes with Histidine Derivatives: Synthesis, Characterization, and Biological Activity
Five novel tin Schiff base complexes with histidine analogues (derived from the condensation reaction between L-histidine and 3,5-di-tert-butyl-2-hydroxybenzaldehyde) have been synthesized and characterized. Characterization has been completed by IR and high-resolution mass spectroscopy, 1D and 2D solution NMR ((1)H, (13)C and (119)Sn), as well as solid state (119)Sn NMR. The spectroscopic evi...
متن کاملSynthesis, characterization and biological activities of some novel isatin derivatives
A series of novel (arylimino-2-oxo-2,3-dihydro-indol-1-yl)-acetic acid N'-(4-aryl-2-yl)-hydrazide derivatives (5a-g) were synthesized. The structures of the newly synthesized compounds were characterized by elemental analysis, FT-IR, H-, C-NMR and mass spectroscopy. The compounds were screened in vitro for antibacterial and antifungal activities against some human pathogenic microorganisms by t...
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ژورنال
عنوان ژورنال: Journal of Advanced Pharmaceutical Technology & Research
سال: 2010
ISSN: 0110-5558
DOI: 10.4103/0110-5558.72428